Streptavidin is a protein (MW of approx. 66,000) made up of four identical subunits, each containing a high affinity binding site for biotin (KD = 10-15 M). It has the same biotin binding properties as avidin, but less non-specific binding is observed. It has been used both in immune assays and genomic assays for target detection.
Spherotech Streptavidin bead surfaces are designed as a matrix for simple and efficient methods such as:
- Protein coated beads for the isolation of biotinylated compounds such as proteins, immunoglobulins, sugars, lectins or DNA/RNA and microRNA
- Magnetic streptavidin coated beads can be used as substrates for both immune assays and genomic assays
- Small fluorescently labeled streptavidin particles can be used as probes for detection.
Select the link below to download the complete SpheroTECHNICAL NOTE. (PDF format)
SpheroTechnical Note #21 will provide the following information: